engineering ebooks

Publisher: Springer
Number Of Pages: 106
Publication Date: 2008-04-21
ISBN-10 / ASIN: 0387786317
ISBN-13 / EAN: 9780387786315
Binding: Hardcover
Product Description: This book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for development and disease in vertebrates. VEGFA controls the proliferation, migration, specialisation and survival of vascular endothelial cells, and it is therefore essential for the establishment of a functional blood vessel circuit. In addition, VEGFA is emerging as a versatile patterning factor for several non-endothelial cell types in vertebrates. Thus, it plays a central role during organ development at multiple levels, including blood vessel growth, vessel-mediated organ induction and tissue differentiation.In writing this book, scientists investigating different aspects of VEGF signalling have come together to highlight the central importance of this growth factor for vertebrate development. From their reviews of our present knowledge, it becomes clear that VEGF’s versatility as a patterning molecule is linked to its expression as several splice forms that interact with a number of differentially expressed signalling receptors. Moreover, by highlighting the present gaps in our knowledge, the authors of this book set direction to future research. It is therefore hoped that this book will provide valuable insights to those already studying VEGF as well as to those members of the scientific and medical community that seek to understand vertebrate development and the origins of disease without specific prior knowledge of the field

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Genomes By T.A. Brown

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* * * Publisher:* Bios Scientific Publishers Ltd
* * * Number Of Pages:* 608
* * * Publication Date:* 2002-06-15
* * * ISBN-10 / ASIN:* 1859962289
* * * ISBN-13 / EAN:* 9781859962282
* * * Binding:* Hardcover
Genomes 2 covers modern molecular genetics from the genomics perspective, incorporating major advances made in the past three years, including the sequencing of the human genome, characterization of genome expressionand replication processes, and transcriptomics and proteomics. The text is richly illustrated with clear, easy-to-follow, full-color diagrams, which are downloadable from the book's website

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Cell Diagnostics: Images, Biophysical and Biochemical Processes in All

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Publisher: Science Publishers
Number Of Pages: 203
Publication Date: 2007-06-30
ISBN-10 / ASIN: 1578085101
ISBN-13 / EAN: 9781578085101

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The Gene Illusion: Genetic Research In Psychiatry And Psychology Under

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Publisher: Algora Publishing
Number Of Pages: 420
Publication Date: 2004-08
ISBN-10 / ASIN: 0875863434
ISBN-13 / EAN: 9780875863436
Product Description:

What are the forces shaping who we are, how we live, and how we act? Are we shaped primarily by our environment, or by our genes? These very old questions form the basis of the "nature-nurture" debate. Increasingly, we are told that research has confirmed the importance of genetic factors influencing psychiatric disorders, personality, intelligence, sexual orientation, criminality, and so on. Jay Joseph’s timely, challenging book provides a much-needed critical appraisal of the evidence cited in support of genetic theories. His book shows that, far from establishing the importance of genes, family, twin and adoption research has been plagued by researcher bias, unsound methodology, and a reliance on unsupported theoretical assumptions. Furthermore, he demonstrates how this greatly flawed research has been used in support of conservative social and political agendas. This is particularly evident in Chapter 2, which contains the only in-depth critical review of the history of twin research ever published. Much of the scientific evidence cited in support of genetic theories has been produced by the fields of behavior genetics and psychiatric genetics. It has been delivered to the public in numerous magazine and newspaper articles, as well as by the authors of several popular books. In particular, studies of twins (both reared together and reared apart) have been cited as providing conclusive evidence supporting the importance of genetic influences on psychological trait differences. The reared-apart twin studies performed by researchers at the University of Minnesota have been the subject of much attention, including stories of individual pairs of "reared-apart" identical twins who, it is claimed, displayed remarkable similarities upon being reunited. Joseph shows, however, that both systematic reared-apart twin studies, and stories about individual pairs, prove little if anything about the role of genes. Schizophrenia is the most studied, and at the same time the most feared and misunderstood, of all psychiatric disorders. Two chapters are devoted to problems with genetic research in this area. One of these chapters reviews schizophrenia adoption research, which includes the well-known and frequently cited Danish-American and Finnish investigations. Another chapter looks into the alleged genetic basis of criminal behavior — an idea more popular today than at any time in the past 60 years. Additional chapters look into other areas of current interest in genetics, such as IQ, the heritability concept, and molecular genetic research. Regarding the latter, in Chapter 10 Joseph concludes that it is unlikely that genes for the major psychiatric disorders exist. In contrast to the bleak view of humans and their future held by people claiming that heredity is of overriding importance, there exists a radically different perspective. Faulty genes are not the cause of human suffering or socially disapproved behavior. Rather, the likely causes are well-known and well-documented psychologically harmful events and environments. This book is essential reading for anyone seeking an alternative to the increasingly popular, yet mistaken view that "genes are destiny."

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Genomics: Fundamentals and Applications

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Publisher: Informa HealthCare
Number Of Pages: 440
Publication Date: 2008-10-09
ISBN-10 / ASIN: 1420067052
ISBN-13 / EAN: 9781420067057
Product Description: This unique new text delivers a solid foundation for understanding the role of genomics in human health and in advances that promise to help improve the quality of human life. Unlike other works that focus mainly on toxico-genomic techniques, Genomics presents a thorough overview of the field in three major sections: 1) fundamentals of genes and genome structure, function, expression, variations, and genomic technology platforms; 2) applications of genomics in drug discovery and drug development, safety evaluation, genomic database maintenance, mining, and analysis, food safety monitoring, and translational toxicogenomics; and 3) how regulatory agencies such as the FDA and EPA use genomic data in their safety evaluation.
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Ecology: Concepts and Applications, 4th Edition by: Manuel C. Molles

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Publisher: McGraw-Hill
Number Of Pages: 608
Publication Date: 2006-10-14
ISBN-10 / ASIN: 0073050822
ISBN-13 / EAN: 9780073050829
Binding: Hardcover

Product Description:

This introductory general ecology text features a strong emphasis or helping students grasp the main concepts of ecology while keeping the presentation more applied than theoetical. An evolutionary perspective forms the foundation of the entire discussion. Evolution is brought to center stage throughout the book, as it is needed to support understanding of major concepts. The discussion begins with a brief introduction to the nature and history of the discipline of ecology, followed by section I, which includes two chapters on natural history—life on land and life in water. The intent is to establish a common foundation of natural history upon which to base the later discussions of ecological concepts. The introduction and natural history chapters can stand on their own and should be readily accessible to most students. They may be assigned as background reading, leaving 17 chapters to cover in a one-semester course. Sections II through VI build a hierarchical perspective: section II concerns the ecology of individuals: section III focuses on population ecology; section IV presents the ecology of interactions; section V summarizes community and ecosystem ecology; and finally, section VI discusses large-scale ecology and includes chapters on landscape, geographic, and global ecology. These topics were first introduced in section I within a natural history context. In summary, the book begins with the natural history of the planet, considers portions of the whole in the middle chapters, and ends with another perspective of the entire planet in the concluding chapter

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The Genetics of Cancer

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Product Detailspages: 338 pages
Publisher: Academic Press
ISBN: 0126398755
Format: PDF
Size: 25.05MB
Credit: grandmaestro
Summary:
Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology
Key FeaturesThe contents include:
* Clonal evolution of the metastasis phenotype
* Cell Cycle regulation
* Apoptosis in tumour growth and metastasis
* Angiogenesis in cancer
* Cell surface glycoproteins and their receptors
* Proteinases and their inhibitors in cancer invasion
* Oncogenes and cancer metastasis
* Developmental genes
* Tumour suppressor genes
* Metastasis suppressor genes
* Dominant metastasis-associated genes
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